The risk of development of atrium fibrillation

Posted on October 1st, 2008 by admin in Medicine

The risk of development of atrium fibrillation increases with increased body mass index

In meta shown that the risk of atrium fibrillation increases with increased body mass index.

Franz Messerli (Columbia University College of Physicians and Surgeons, New York, USA) combined data 5 population studies that included 78,602 adults and 11 studies involving 44,647 patients, endured surgery.

In the population as a whole, the availability of excess body weight was associated with increased risk of FP 39%, while the presence of obesity - by 87%. Among men, the corresponding figures were 40% and 71%, and among women 44% and 101%.

At the same time, patients, endured surgery this relationship is not revealed.

Snoring and chronic bronchitis are linked

Posted on October 1st, 2008 by admin in Articles

Snoring and chronic bronchitis are linked

People Snoring in their sleep, often ill with chronic bronchitis, claim researchers from the Korea University (South Korea).

The study lasted four years, was attended by 4270 persons, among whom were suffering as well and not suffering from snoring people. During the observation period from 314 of them had first been diagnosed with chronic bronchitis.

After taking into account information on the age and known risk factors for chronic bronchitis (eg, smoking), researchers found that snoring can also contribute to the development of the disease. In particular, people Snoring from time to time (up to five nights a week), chronic bronchitis occurred 25% more often than not with people suffering from snoring. Those who hrapel almost every night (six to seven nights a week), the risk of bronchitis increased by 68%, researchers reported.

The reason the relationship between Snoring and bronchitis is not yet clear. Scientists believe that the vibration of upper respiratory tract, with snoring may in some way contribute to the development of inflammation, said the journal Archives of Internal Medicine.

The conflict can positively affect health and longevity Rights

Posted on October 1st, 2008 by admin in Medicine

The conflict can positively affect health and longevity Rights

Study University of Michigan showed that in some circumstances, conflict is good for human health and longevity.

In the study, scientists monitored the 192 family pairs over 17 years. For all the basic criteria - age, social status, state of health, harmful and useful habits, etc. - surveyed couples were virtually identical.

All families have been divided into four groups based on one criterion: how they resolve conflicts. The first group included those families where the wife attacking each other. The second - the family, where men insult spouses, in the third - pairs, where, by contrast, the wife of an affront to their husbands. A fourth group were identified as those families where the wife hide from each other by their protest, disappointment and resentment.

This observation led to an unexpected conclusion: if couples prefer to settle the case and the world will not allow their emotions, the rate of early death among them twice, compared to families where one or another form of emotion spills.

The authors of the study suggest that the reason may be cumulative stress, however, to confirm this hypothesis will require further study.

Of the marine bacteria are powerful new antibiotics

Posted on October 1st, 2008 by admin in Medicine

Of the marine bacteria are powerful new antibiotics
A group of researchers led by Dr. William Fenical from the Scripps Institution of Oceanography, California, USA, found in marine bacteria genus Streptomyces two substances that have strong antimicrobial activity is still unknown structural type.

The new structural class of antibiotics called marinopyrroles, a marine pyrrol. Both Funds American biochemists substances - marinopyrroles A and B - composed of two pyrrol fragments, nitrogen, carbon. In each of pyrrol fragments of a high degree of substitution of hydrogen for chlorine. Previously, such structures were not known in living organisms. More high antimicrobial activity showed chiral isomer marinopyrroles A, obtained by researchers in the laboratory. The new antibiotics, their isomers and structural modifications will find application in medicine.

A study published in the journal Organic Letters.

A new approach to the regeneration of retinal

Posted on September 1st, 2008 by admin in Articles

In experiments at the aquarium fish ryori data found that in the eyes are special cells to regenerate the retina and restore sight, even after serious injuries. Scientists believe that these cells - they are called “myllers glial cells” - will help regenerate damaged retina and in humans.

Damage to the retin - the main cause of blindness. The cause of these injuries may have different illnesses, such as yellow spots degeneration, glaucoma or diabetes; in the UK three-quarters of cases of blindness caused by such diseases.

Specialists from the UCL Institute of Ophthalmology and Moorfields Eye Hospital studied myllers glial cells in the eyes of people aged 18 to 90 years. It was shown that this population of cells has the properties of stem cells and they can differentiate into different types of cells of the retina. In addition, the researchers managed to obtain in the culture of these cells all types of neurons, represented in the retina.

When checking for a rat model of retinal disease was discovered that myllers glial cells migrate in the retina and acquire the characteristics of the surrounding neurons. At present, scientists are looking for an opportunity to use this approach in treating people. You can grow these cells in the laboratory and then transplanted, but you can find a way to stimulate their growth and development in vivo, that regeneration was from their own cells damaged eye.

myllers cells can be used for the treatment of people losing or have lost their eyesight due to illness, destroying the retina. It may preserve such cells in a special bank and conduct allogeneic transplants or use their own cell patients. The latter has the advantage that there is no immune response.

Although myllers glial cells are present in the eyes of everyone, not understand why some people are automatically restore the damaged retin, and others - none. Perhaps in normal adult retin, there are some external mechanisms that prevent these cells share.

Next objective research - to determine what factors are blocking the natural regeneration. As has become clear mechanism myllers cells, scientists have already approached the noticeable development of a method of cell therapy retinal diseases. Experts expect that such a method would be established within 5-10 years, will be used patients’ own cells.

According to Science Daily

The cells of fetal aorta suitable for the treatment of ischemia

Posted on September 1st, 2008 by admin in Articles

The formation of new blood vessels in embryonic or fetal tissue is due immature vascular cells - angioblastam. This process is still little understood.

The team of Italian scientists from Milan Carlo Besta Neurological Institute identified the population of cells predecessors vessels (vascular progenitor cells (hVPCs)) human fetal tissue in the aorta. This fabric is made up of undifferentiated cells mezenhimalnyh, while expressing endothelial as well miogennye markers. In terms of cultivation, enabling differentiation of cells (with the help of vascular endothelial growth factor-A or trombotsitarnogo growth factor-beta), of hVPCs formed a mixed population, composed of mature endothelial cells and cells of vascular wall. In hVPCs neadgezivny culture, and when growing in three-dimensional collagen gel organized in a tube resembling mature vessels. Konditsioneer hVPCs Wednesday contains angiogennye factors (vascular endothelial growth factor-A and angiopoetin-2) and stimulates the proliferation of endothelial cells.

When the transplantation of small quantities of hVPCs in ischemic limbs immunnodefitsitnyh mice, there was significant improvement in reducing deaths and neovaskulyarizatsii endothelial cells and myocytes, resulting in a considerable alleviation of ischemia. Thus, was shown therapeutic efficacy of these cells.

The authors conclude the work that fetal aorta is a good source of human vascular cells for research of their predecessors phenotypic and functional properties and for use in cell therapy.

Materials research presented in the article Invernici G, et al. Human fetal aorta contains vascular progenitor cells capable of inducing vasculogenesis, angiogenesis, and myogenesis in vitro and in a murine model of peripheral ischemia. Am J Pathol. 2007 Jun; 170 (6) :1879-92.

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Posted on September 1st, 2008 by admin in Uncategorized

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